Name: Rachel Guest

Theme: Non-Hodgkins Lymphoma

OPTION LIST

A	Watchful waiting	I	High dose methylprednisolone
B	Radiotherapy (Mantle area)	J	Alpha Interferon with Imatinib
C	Radiotherapy (Inverted Y area)	K	CHOP with autologous stem cell transplantation
D	Radiotherapy and Rituximab	L	Palliation
E	Rituximab alone	M
F	Single agent chemotherapy	N
G	Intensive combination chemotherapy (CHOP)	O
H	CHOP with Campath (anti-CD25 antibody)	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 60 year old man with painless cervical lymphadenopathy, and normochromic, normocytic anaemia found on full blood count.

2. A 65 year old woman with follicular lymphoma with widespread lymphadenopathy, splenic infiltration and gastrointestinal involvement seen on CT.

3. A 50 year old man with mediastinal lymphadenopathy, hepatosplenomegaly, fever and drenching night sweats. On lymph node biopsy, large, primitive blastic B cells were seen with a loss of nodular architecture.

4. A 50 year old man, experiencing fevers, weight loss and lymphadenopathy following radiotherapy for previously diagnosed Non-Hodgkins Lymphoma.

5. A 50 year old man with cervical, mediastinal and inguinal lymphadenopathy, and hepatosplenomegaly. Histology revealed small, well-differentiated B cells.

ANSWERS

1. B

2. A

3. G

4. K

5. A